Florisil is a magnesia-loaded silica gel. Like silica, it is extremely polar in nature and ideal for the isolation of polar compounds from nonpolar matrices. The larger particle size of the sorbent enables fast flow for large sample volumes and therefore can be an attractive alternative to silica if the sample matrix is particularly viscous.
Alumina, like silica, is an extremely polar sorbent. The alumina surface tends to be slightly more stable under high pH conditions than unfunctionalized silica. The small particle size of the Bond Elut Alumina range ensures high extraction efficiency even when small bed masses are used.