Accurate results are crucial for blood alcohol content analyses. Check out what we recommend for achieving the chromatography you need
Small leaks can turn into costly repairs. If you don’t know where you should regularly be checking for leaks in your GC system, then this blog is for you!
As ilicit drugs continue to be synthesized, the demand for analytical methods that can ensure accurate results for comprehensive drug lists is at an all time high. We highlight some of the newest drugs on the market.
Well plates provide a number of advantages over chromatography vials for high throughput laboratories. In this blog we discuss one significant advantage of our TrueTaper plates.
How do you reduce matrix interference when working with biological samples. In this clinical research application, we discuss a simple method for preparing samples for vitamin D analysis.
What happens if the system you’re using to analyze PFAS is affecting your results? Find out how you should be reducing that risk.
Glass vials are very common among chromatographers, but how do you know what type of glass you should be using? Let’s find out!
Many chromatography labs also have methods run on an ICP-MS. Discover common applications for inductively coupled plasma mass spectrometry (ICP-MS), and how it differs from chromatography and other methods of analysis.
Do your syringe filters clog up easily from extra dirty samples? Consider a glass pre-filter syringe filter to filter samples quicker for a smoother sample preparation.
One simple way to protect yourself and others in the lab is by complying with safety guidelines. We make it easy to collect and handle HPLC solvent waste with our safety waste containment kit.
If you’re looking for a way to make plumbing your LC system easier, look no further. Discover why customers prefer Agilent capillary tubing to regular SS or PEEK options.
Whether you’re concerned about conserving helium usage in the lab, or that samples may be contaminated, checking for gas leaks is essential for optimal GC performance.
With prescription drug abuse still at record highs, an LC-MS/MS methodology was developed for 231 drugs and drug metabolites with a the retention required for the wide range of compound classes tested.
Etg and Ets are polar analytes, and detection on a reversed phase column can be difficult, so we recommend a column specifically for polar analytes.
In high throughput laboratories, excess time and money spent on analyses is compound by the number of runs/day. Having a streamlined, cost effective workflow is very important.
With ongoing helium shortages causing expensive pricing and rationed supplies, now is a perfect time to consider switching to alternative carrier gas options.
High recovery vials are necessary for labs that need to get the last drop of sample, and we have them available at a great price
Are you wondering how long your column will last and how many injections you can get on an HPLC column? Chrom Tech's professionals will help you in our detailed guide here.
Superficially porous particles are the industry standard and here we discuss how to switch to a SPP column.
Do you know the benefits and drawbacks of metal or polymeric fittings? We compare the options in the latest blog.
We dive into some of the more complex methods that scientists use for solving real crimes every day.
We dive into some of the more complex methods that scientists use for solving real crimes every day.
If you’re vials are on backorder, you’ve come to the right place. Chrom Tech has vials for your lab, ready to ship on a moment’s notice.
HPLC connections can be intimidating, but we’re here to simplify them for you. Here is a simple way to connect your syringe to tubing or directly to your LC pump.
What’s a fast and easy way to reduce the frequency of replacing your HPLC column? Bethany walks us through the benefits of using a guard column.
With so many vials to choose from, we break down the consideration of vial material to make your decision between glass or plastic vials easy.
Understanding what fittings to keep on hand is important to keep your HPLC up and running when you need it. Check out our list of essential HPLC fittings and other chromatography consumables.
Researchers use an Agilent HPLC and Poroshell Column to semi-automate synthetic opioid detection methods.
How do you choose between syringe filters and filter vials? There are benefits to both, so dive into the options in this blog!
Headspace GC can be an excellent tool for analyzing volatile compounds in complex mixtures. In this article we discuss some of the applications where headspace GC is commonly used.
Sometimes it’s necessary to use an insert in your autosampler vial. Here we discuss how to choose the best insert for your chromatography application.
Biotechnology applications of HPLC determine the success of food, agriculture, medicine, research, and more. Discover how and why HPLC is used for such an important industry.
There are a few things to consider before purchasing an HPLC pump. Here we discuss the questions we always ask our customers when determining what pump will be best for their application.
Ask Ben! If you’re one of the many people overwhelmed by all the GC inlet liner options, you’ve come to the right place!
Explore the different options for chemically compatible, transparent tubing, designed for low and medium pressure applications. See what option will work best for your application.
The ability to properly make HPLC connections is an imperative skill to have if you use HPLC. In this guide, we cover the steps for swaging HPLC fittings onto your tubing.
Every lab produces waste, and it's crucial that they dispose of the waste the right way. Read here to learn how to dispose of HPLC waste properly.
Headspace vial caps are essential accessories in chromatography labs. Our experts help you choose the right cap for your application in our guide here.
Choosing a syringe for HPLC or GC can seem daunting, especially when you see how many options there are. There are some helpful considerations discussed in this blog to help you decide what syringe type will work best for your application.
96 well plates are one of the most used items in a lab, but what do the different shaped bottoms mean? Our team answers that question and more here!
Silane-treated vials are full of unique benefits, especially for trace analysis quantitation. Read here to learn the advantages of these vials from our experts.
HPLC has various applications; one of the unique uses is fuel ethanol fermentation analysis. Learn how this works and more from our experts here.
Chrom Tech offers various glass well plate inserts. If you want to learn the benefits of glass well plate inserts, read our comprehensive guide here.
Is your lab preparing to offer carbohydrate analysis? Ensure you're using the correct HPLC column for the best results. Read here to learn from our experts.
PEEK tubing is essential for every laboratory, as it makes excellent HPLC connections. Learn how to make these connections from our experts here.
HPLC pumps must be able to run trouble free 24/7/365. So, in order to keep your pump in “prime” condition, we recommend planning routine maintenance and keeping commonly replaced items in your lab drawer.
Chrom Tech 96 well microplates conform to the ANSI/SLAS footprint specifications, ensuring that they are compatible with all major microplate readers and automation technologies. ANSI/SLAS designates that the plate length is 127.76mm +/- 0.25mm and the plate width is 85.48mm +/- 0.25mm.
Long lead times have been a big problem for many labs. We're here to offer our suggestions on how to reduce those lead times for products in your lab, and get the products you need when you need them. In our latest blog, we dive headfirst into some simple steps you can take to reduce lead times in the lab.
It is important to prime your HPLC pump to ensure that only the solvent you want flowing through the pump is present. Therefore, when installing a new pump, taking a pump out of storage, or changing solvents, it is important to prime the HPLC pump.
PFAS testing has become increasingly popular work in laboratories, but you must use the proper vial. Read here to learn the best vials to use for PFAS testing.
If you work in a laboratory, you must know what causes peak tailing in HPLC. To help you understand more, our experts put together a detailed guide here.
PEEK tubing is essential in laboratories. If you'd like to learn what PEEK tubing is and its different types, read our comprehensive guide here.
If you're curious what the is difference between UHPLC and HPLC, our team has the answer. Read here to learn directly from our experts about UHPLC and HPLC.
If you'd like to learn how HPLC pumps were used in the production of Lipid-based Nanoparticles for delivering mRNA-based vaccines, our experts explain here.
Work in a chromatography lab? Make sure you understand what endcapping is in HPLC columns. Our experts break down everything you need to know here.
Anyone who works in a lab should know HPLC pump care and troubleshooting to ensure peak performance. You can learn more in our comprehensive guide here.
If you work in a laboratory, you should know how to regenerate a C18 HPLC column. The experts at Chrom Tech have you covered in our detailed guide here.
On April 22nd, people across the globe will initiate sustainability efforts, connect with nature, and educate others on how we can reduce our carbon footprint in celebration of the 51st annual Earth Day. This year, the theme is “Restore Our Earth”, and we would like to hear what others are doing to participate. Chrom Tech founder, Steve Pierson sought after ways to reduce waste, re-use materials, and utilize recyclable products wherever possible at the company, many of which are still everyday practices today.
In general, modern chromatography liquid autosamplers accept 12 x 32mm vials, so we will assume that a 12 x 32mm vial is compatible with your autosampler (Headspace autosamplers accept 20mm wide autosampler vials). Here, we have outlined the simple steps in selecting the best chromatography vial for your analysis.
Superficially porous particles (SPPs) have a solid core surrounded by a thin, porous shell rather than porous throughout the entire particle, as is the case in traditional, fully porous particles. The solid core limits diffusion distance and improves separation speed. Superficially porous particles also have a narrow particle size distribution, improving efficiency and resolution. Another advantage of superficially porous particles is they can be used on both HPLCs and UHPLCs. Because of the variety of phases now available and the compatibility with both new and older HPLC systems, superficially porous columns are many chromatographers’ first choice when developing a new HPLC method.
Hydrogen is increasing in popularity in the GC world as a carrier gas. In this blog, will explore why more and more laboratories are turning to hydrogen.
In order to understand which pumps are used in HPLC, we will first explore why high pressure is needed in HPLC.
It is recommended to change your HPLC pump’s piston seals during planned preventative maintenance. With regular pump usage, this is recommended every six months. And, remember, if you have a dual-piston pump, you have two piston seals to replace.
Did you know?! 100% of our salesforce has work experience in a chromatography laboratory. Plus, our customer service works hard to ensure on-time delivery. 98% of our orders ship on time – we work to get your supplies to you by the estimated delivery date. Our loyal customers receive their complete orders within 2 days, on average.
HPLC Column temperature affects retention time, selectivity, peak shape, and pressure. Let’s look at this in more detail.
Inductively Coupled Plasma - Mass Spectrometer; that is a mouthful. ICP-MS for short is a more recent advancement in analytical instrumentation designed to detect low and trace levels of metals in various samples in their native form or as part of a compound. These samples can be derived from everyday things our families encounter.
If you're looking to understand how a pulse dampener works in an HPLC pump, the experts at Chrom Tech have you covered. Learn more in our detailed guide here.
Proteins make up every living organism and as you can imagine, many industries (pharmaceutical, clinical, environmental, etc.) rely on understanding them. One means of analyzing a protein is through LC-MS. A difficult question that researchers often get hung up on is “What LC column should I use?”.. The answer is: it depends. It depends on the type of experiment you are going to be performing, the type of protein you are working with, and other factors. Here we will break down the ideas behind this question through the topics below.
PEEK tubing has its own strengths over stainless steel tubing in HPLC, so when should you use PEEK tubing? Our experts discuss everything you need to know here.
If you're wondering if there is a universal membrane for syringe filters, we've got you covered. Learn the answer and more in our comprehensive article here.
All lab professionals must know the types of fittings that are used in HPLC. The experts at Chrom Tech cover everything you need to know in this detailed guide.
Laboratories should follow the EPA's recommendations when it comes to washing HPLC vials. You can learn the EPA's guidelines in our comprehensive guide here.
All laboratory professionals should understand particle and pore size in HPLC columns. Read our comprehensive guide here to learn from our experts.
Have you always wondered what 96 well microplates are used for? We've got you covered. The experts at Chrom Tech break down everything you need to know here.
Although hydrogen gas cylinders are commonly found in the laboratory, they present a variety of safety risks and unexpected instrument downtimes due to inconsistent delivery schedules. These issues can be eliminated by switching to an on-site gas generator. Read more to discover the answers to frequently asked questions concerning the safety of Hydrogen generators.
Lab professionals must understand the difference between a union and an adapter in HPLC. Read our guide to learn what makes unions and adapters different.
Every lab professional must understand HPLC column care and maintenance. Our experts at Chrom Tech cover just that in our guide; read here to learn more.
If your lab uses gas chromatography, learn why you should use GC derivatization reagents. The experts at Chrom Tech break down everything you need to know here.
If you're looking to learn how to streamline your sample preparation workflow, we have you covered. Read here to learn from the experts at Chrom Tech.
Choose Chrom Tech economical HPLC syringe filters to remove particulates from your liquid samples prior to injection on your HPLC.
HPLC pumps or solvent delivery pumps can be used for many applications, not just specific to chromatography applications.
Liquid liquid extraction (LLE) is a labor-intensive method in which you are separating compounds into two immiscible liquids: the aqueous layer and an organic solvent layer.
By definition, pressure is inherent in HPLC systems because solvent is being pumped through a packed bed of small particles.
Sample preparation is an important step in chromatography, maximizing system uptime and extending column lifetime. Here are a few fundamental sample preparation processes.
Acetonitrile (ACN) and methanol (MeOH) are the most common organic modifiers in reversed-phase chromatography. Both solvents offer certain advantages and disadvantages. This guide takes a deeper look at acetonitrile vs. methanol for reverse phase chromatography.
Outgassing and bubble formation can negatively impact the flow of the mobile phase and the analysis of analytes. Degassing is used to prevent these issues.
Analytical columns can fail over time due to particulates, solvent impurities, and sample contents. Filters and guard columns protect the column from damage.
Is buying pre-cut stainless steel tubing worth the premium? In this blog, we discuss the benefits of pre-cut vs. cutting your own length of tubing.
One of the biggest concerns in our world today is the state of the environment. Every day, our planet faces new challenges contributing to climate change, deforestation, and ozone depletion.
Many factors play a role in deciding which vial is best for your needs such as sample volatility, sample amount, and light sensitivity. Choosing the right vial is imperative to increasing ROI and operability and decreasing sample degradation due to improper collection or storage. Follow this guide for tips on how to select chromatography vials for the best results...
Liquid Chromatography can be achieved through many methods including reverse-phase and hydrophilic interaction liquid chromatography (HILIC). Liquid chromatography is a form of column chromatography that uses an HPLC pump to pump an analyte in a solvent (the mobile phase) at high pressure through a column (stationary phase) to separate...
Vials and 96-well plates are standard consumables used in chromatography. While vials were previously the industry standard, well plates have become more popular in recent decades. Both vials and well plates still hold advantages that make them viable options in chromatography processes. Vials vs. 96-well plates for chromatography is a debate worth investigating before deciding which to use in your lab.
Chromatography is a vital tool used in many industries to determine the composition of a mixture. Chromatography is widely known for its role in scientific research, although it holds importance in other industries. Chromatography plays a vital role in industries we interact with quite often. Pharmaceuticals, clinical trials, environmental and chemical safety, food and beverage, drug testing, forensics, petroleum creation, and molecular biology are some of the most common uses of chromatography.
The COVID-19 pandemic has created unprecedented struggles across the world due to symptom variability and high spread rate. As COVID-19 continues to surge through the U.S., there is an increasing need for technology that will help us understand viruses like COVID-19 faster.
