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  • LC and GC Supplies in Stock
  • Autosampler Chromatography Vials & Accessories
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    • HPLC Vials & Closures
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      • Screw Thread Vials
      • Snap Top Vials
      • Max Recovery Vials
    • GC Vials & Closures
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      • Crimp Top Vials
      • Headspace GC Vials
    • 12 x 32 mm LC and GC Autosampler Vials, Closures & Inserts
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      • 8-425 Standard Screw Thread Vials
      • 9 mm Wide Mouth Screw Thread Vials
      • Pre-Loaded Inserts in 11 mm Autosampler Vials
      • 11 mm Wide Mouth Snap Vials
      • 11 mm Standard Crimp Vials
      • 11 mm Wide Mouth Glass Vials
      • PFAS Testing
    • 15 x 45 mm WISP and Shimadzu Vials, Closures & Inserts
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      • Standard Screw Thread Vials
      • Snap Seal Vials
    • Headspace Chromatography Vials and Closures
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      • Crimp Vials
      • Screw Thread Vials
      • PolyMag Screw Caps
    • Miscellaneous Chromatography Vials
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      • Silanized Vials
      • Storage Vials, Caps & Seals
      • V-Vial Reaction Vials
      • Vial Racks
      • Mininert Valves for Vials
      • EPA/VOA Vials
      • Shell Vials
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    • Low Adsorption Vials
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      • Special Surface Properties
      • Screw Thread RSA Vials
      • Snap Top RSA Vials
    • Agilent Vials
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      • 12 x 32 mm, Wide Mouth Screw Thread
      • Wash Vials
      • 12 x 32 mm, Wide Mouth Crimp
      • Headspace Vials
  • 96-Well Plates
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    • 96 Deep Well Plates
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      • Glass Inserts in Plates
      • Chrom Tech MS Polypropylene Plates
      • 96 Well ELISA Plates
      • PCR Plates
      • Pulled Point Inserts in Plates
      • Reservoir Trough Polypropylene Plates
      • Greiner Bio-One Plates
      • Friction Seals, Pierceable Cap Mats
    • Sealing Films & Foils
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      • Heat Sealing Film and Foil Rolls
      • 96-Well Sealing Film & Tape
      • Porvair Heat Seals & Foils
    • 96-Well Microplate Instrumentation
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      • Plate Heat Sealers
      • Positive Pressure Processor
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  • Sample Preparation
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    • Laboratory Filtration Supplies
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      • Centrifuge Filter Tubes
      • Syringe Filters
      • Membrane Filters
      • Filter Vials
      • Filter Plates
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      • Captiva Filtration
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        • Captiva EMR-Lipid
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        • Agilent Econofilters
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    • Solid Phase Extraction
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      • Agilent Bond Elut Plexa Polymeric SPE
      • Agilent Bond Elut Reversed Phase (Non-Polar) Silica SPE
      • Agilent Bond Elut Ion Exchange Silica SPE
      • Agilent Bond Elut Ion Mixed Mode Silica SPE
      • Agilent Bond Elut Inorganic SPE
      • Agilent Specialty SPE
      • Bond Elut Lipid Extraction SPE
    • Supported Liquid Extraction
    • Instrumentation
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      • Evaporators
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        • Bar Vap
        • Cerex Concentrator 48
        • Chrom Tech Low Cost
        • Porvair
      • Positive Pressure Processor
      • Vacuum Manifolds
      • Homogenizers
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        • BeadBlaster 24
        • BeadBug 6
        • BeadBlaster 96
      • Dried Blood Spot Card Punch
      • Vortex Mixers
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        • BioMixer
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        • Orbital Shakers & Rockers
        • Vornado
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  • HPLC Columns
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    • Agilent for Small Molecule
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      • InfinityLab Poroshell 120
      • ZORBAX Eclipse Plus
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      • ZORBAX 80Å StableBond
      • ZORBAX 80Å Extend-C18
      • ZORBAX Bonus-RP Columns
      • ZORBAX Eclipse PAH
      • Zorbax HILIC Plus
      • Zorbax NH2
      • ZORBAX Rx
      • Pursuit XRs
      • Polaris
    • Agilent BioHPLC
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      • Poroshell 300
      • AdvanceBio RP-mAb
      • AdvanceBio Glycan Mapping
      • InfinityLab Poroshell 120 AdvanceBio Peptide Mapping
      • PLRP-S
      • Zorbax 300A Stablebond
      • AdvanceBio SEC
      • ProSEC 300S
      • Bio SEC-3
      • Bio SEC-5
    • Agilent for GPC/SEC
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      • Aqueous GPC/SEC Columns
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        • PL aquagel-OH SEC columns
        • PolarGel GPC Columns
        • PL Rapide
        • Aqueous Polymer Standards
      • Organic GPC/SEC Columns
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        • PLgel MIXED Columns
        • PLgel MIXED LS
        • PLgel MiniMIX Narrow Bore
        • PLgel Olexis Columns
        • PLgel Individual Pore Size & Preparative Columns
        • HFIPgel Columns
        • PL Rapide Columns
        • PlusPore Columns
        • EnviroPrep Columns
        • Polystyrene Standards
        • Polymer Standards
    • Concise Separations
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      • Carbohydrate Analysis
      • Organic Acid Analysis
      • Protein Analysis
      • Amino Acid Analysis
      • Ion Analysis
    • Hamilton
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      • Reversed-Phase
      • Anion Exchange
      • Cation Exchange
      • Ion Exclusion
    • Imtakt
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      • Presto FF-C18
      • Dacapo DX-C18
      • Cadenza CD-C18
      • Intrada Amino Acids Separation Column
      • Scherzo C18 Mutli-Mode Column
    • Jordi
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      • Jordi Resolve Aqueous GPC
      • Jordi Resolve Organic GPC
    • Regis
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      • Regis Pirkle Chiral HPLC Columns
      • Immobilized Artificial Chromatography
    • Restek
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      • UltraShield UHPLC Precolumn Filter
      • Raptor LC Columns
      • Ultra HPLC
      • Force
      • Roc
    • Millipore Sigma
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      • Ascentis Express
    • Thermo Scientific
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      • Accucore
      • Hypersil Gold
    • Vydac
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      • HPLC/MS Columns
      • 201TP and 202TP
      • Columns for Peptides & Polypeptides
    • Zirchrom
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      • ProTain In-Line Protein Removal System
      • Zirconia Based HPLC Columns
  • GC Columns
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    • Agilent J&W GC Columns
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      • DB-WAX Ultra Inert
      • DB-1ms Low-Bleed
      • DB-1ms Ultra Inert
      • HP-1ms Low-Bleed
      • HP-1ms Ultra Inert
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    • Agilent J&W Polysiloxane
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      • DB-1
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      • Carbowax 20M & HP-20M
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    • Agilent J&W Specialty Columns
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      • High Temperature
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        • DB-1ht
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      • Petroleum
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        • CP-Sil PONA CB
        • HP-PONA
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        • DB-2887
        • DB-HT SimDis
        • CP-SimDist
        • CP-TCEP for Alcohols in Gasoline
        • Select Low Sulfur
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      • Select Biodiesel
      • Amines
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        • CP-Volamine
        • CP-Sil 8 CB Amines
      • Pesticides
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        • VF-5 Pesticides
        • VF-1701
        • DB-1701P
        • DB-608
      • PAH
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        • Select PAH
        • DB-EUPAH
      • Semivolatile
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        • DB-UI 8270D
        • DB-5.625
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        • DB-624 UI
        • DB-624
        • CP-Select 624 CB
        • DB-VRX
        • HP-VOC
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    • Restek High Performance GC Columns
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      • Rxi-1301Sil MS
      • Rxi-Guard
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      • Rxi-35Sil MS
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    • Restek General Performance
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      • Rtx-1301
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      • Rtx-2330
      • Rtx-35
      • Rtx-35 Amine
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  • HPLC Accessories
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    • HPLC Instrumentation
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      • Chrom Tech Pumps
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        • Single Piston Isocratic Pumps
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          • Low Profile M1 Class
          • MXT MODEL
          • LST MODEL
        • Dual Piston Isocratic Pump
        • Constant Pressure Isocratic Pump
        • High Flow Dual Piston Pumps
        • Super Critical Fluid Pumps
        • Flash Pumps
        • Pulse Dampener
      • Vacuum Degasser
      • Column Heaters
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        • H-705 Column Oven
        • H-105 Column Heater
        • Column Hot Sleeve
      • Detectors
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        • UV/VIS
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          • Fixed Wavelength
          • Variable Wavelength
          • Multi Wavelength & Diode Array
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            • FLASH 10MWD
            • FLASH 14 DAD
        • Refractive Index
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          • RI-S2020
      • Fraction Collectors
      • DataApex Clarity Software
      • Post Column Derivatization
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        • Application Kits, Reagents & Columns
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          • Amino Acid Analysis Kits
          • Pesticide & Herbicide Analysis Kits
        • Pickering PINNACLE PCX System
        • Pickering VECTOR PCX System
        • Sensivate System
    • HPLC Accessories - Empty Columns
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      • Glass Columns
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        • EZ Column
        • EZ Solvent Plus Columns
        • Replacement Parts, EZ & Solvent Plus
      • SS Columns
    • Valco Fittings & Accessories
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      • Internal Unions
      • Internal Reducing Unions
      • Internal Reducers
      • Stainless Steel Fittings
      • Syringe Adapter
      • Tees
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      • National Pipe Thread Adapters
      • Valco Sample Loop for C6W
    • HPLC Fittings
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      • Flangeless Fittings
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        • Flangeless
        • Super Flangeless
      • National Pipe Thread Adapters
      • Large Bore Fittings
      • Fingertight Fittings
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        • Rheodyne RheFlex
        • Agilent A-Line Quick Connect Fitting
        • Upchurch One-Piece
        • Upchurch Two-Piece
        • SealTight
        • LiteTouch
      • Stainless Steel Fittings
      • UHPLC Fittings
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        • Agilent InfinityLab Quick Connect Fitting
        • Agilent A-Line Quick Turn Fitting
        • Idex VHP Fittings
        • Optimize EXP2 Fittings
        • PK VHP Fittings
      • Agilent InfinityLab Quick Connect Fittings
      • MicroTight Fittings & Sleeves
      • Tubing Sleeves
      • Plugs & Caps
      • Tools
    • HPLC Connectors/Adapters
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      • Unions, Tees & Crosses
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        • Union, High Pressure
        • Union, Low Pressure
        • Tees & Crosses, High Pressure
        • Tees & Crosses, Low Pressure
        • Manifolds
      • MicroTight Connectors
      • MicroTee & Cross
      • NanoPort Assemblies
      • Mixing Tees
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        • ASI Static Mixers
        • Idex Static and Mixers
      • Threaded Adapters
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        • English Threads
        • Metric Threads
      • Luer Adapters & Luer Fittings
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        • LuerTight Fittings
        • Quick Connect Adapters
      • Barbed Adapters & Connectors
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        • Barbed Connectors
        • Luer to Barb Adapters
        • Swivel Barb Adapter
        • Thread to Barbed Adapter
      • Peristaltic Tubing & Conical Adapters
    • Polymeric Liquid Chromatography Tubing
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      • PEEK Tubing
      • FEP Fluoropolymer Tubing
      • ETFE Tubing
      • PFA Tubing
      • Tubing Cutters
    • High Pressure HPLC Tubing
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      • VICI Precut Stainless Steel Tubing
      • 316 Stainless Steel Tubing
      • Tubing Cutters
      • Fused Silica Tubing
      • Hastelloy C Custom Length Tubing
      • Agilent Miscellaneous Capillaries
      • PEEKsil Tubing
    • Chromatography Solvent Containment
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      • Solvent Waste Container Kit
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        • System kit
        • Replacement Parts
        • Accessories
      • Solvent Waste Manifolds
      • Popular Manifold Fittings and Tubing
      • Vaplock Solvent Waste Manifold Caps for GL45, GL38 and 38-430
      • Vaplock Solvent Waste Manifold Caps for Carboy Containers
      • Mobile Phase/Storage Bottles
      • Glass Filtration Assembly
      • Bottle Caps
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        • IDEX Bottle Caps
        • Vaplock Bottle Caps & Evaporation Control Valves
        • Omnifit Q-Series Bottle Caps
      • Solvent Filters and Inlet Filters
    • Valves
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      • Injection Valves
      • Sample Loops
      • Switching Valves
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      • Micro-Splitter Valves
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      • RheBuild Kits, Rapid Replacement Pods & MXX Replacement Fittings
      • Rotor Seals & Stators
      • Valve Accessories
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        • Syringes for Manual HPLC Valves
      • Hamilton Manual Valves
      • Inline Check Valves
      • Back Pressure Regulators (BPRs)
      • Pressure Relief Valves
    • Inline & Precolumn Filters
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      • Agilent Quick Connect Inline Filters
      • Inline Solvent Filters
      • Standard Precolumn Filters
      • Replacement Frits
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        • PEEK frits
        • Stainless Steel frits
      • EXP® Pre-Column Filter Holder
      • Biocompatible Precolumn Filters
      • Precolumn MicroFilters
      • Frit-In-A-Ferruleâ„¢
    • Guard Columns
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      • EXP Guard Column Cartridges
      • IDEX Guard Columns
      • Capillary Sample Trap Columns
      • Agilent AdvanceBio Desalting-RP Cartridges
    • LC Instrument Replacement Parts
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      • Agilent Parts for Agilent HPLCs
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        • Loop Capillaries
        • Tubing, Connections, & Tools
        • 1260 Infinity Isocratic LC Supplies
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        • Needles and Needle Seats
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      • Cartridge for Opti-Max Housing
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  • Chrom Tech Pumps
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    • Single Piston Isocratic Pumps
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      • Low Profile M1 Class
      • MXT MODEL
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    • Agilent Consumables
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      • Bulk GC Supplies
      • Inlet Septa
      • Inlet Liners
      • Specialty Injection Liners
      • Gold Seals for Split/Splitless Inlets
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      • Capillary Column Ferrules and Nuts
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    • Agilent Instrument Replacement Parts
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      • Headspace Vials
      • 7890B/7890A/6890 GC Supplies Quick Pick
      • 7890/6890/6850 Split/Splitless Inlet Supplies
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    • Restek Consumables
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      • Topaz Inlet Liners
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        • For Agilent
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      • Restek Gas Leak Detectors
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        • Polyarc Systems
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      • Agilent Gas Clean Filters
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    • Regis GC Derivatization Reagents
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      • Silylation Reagents
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    • Hamilton Manual Syringes
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        • 7000 Series
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      • CTC LC Autosampler Syringes
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      • SoftGrip Single Channel Pipettes
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      • MicroLab Dual Syringe Diluters
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      • Regis Sulfonates (S-Series) For Basic Compounds
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      • Amino Acid Analysis Kits
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  • HPLC Waste Containers and Lab Safety Cabinets
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        • Sure-Grip EX Safety Cabinets
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        • Double-Duty Sure-Grip EX Safety Cabinets
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        • Vertical Drum Sure-Grip EX Safety Cabinets
        • Drum Cabinets Accessories
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    • HPLC Safety Waste Containers
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      • Safety Waste Containment Kit
      • HPLC Waste to Drum Kit
  • Chromatography Across Industries
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      • COVID-19 Antibody Research
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  • LC and GC Supplies in Stock
  • Autosampler Chromatography Vials & Accessories
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      • 8-425 Standard Screw Thread Vials
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    • Home /
    • HPLC Accessories /
    • Guard Columns

    Guard Columns

    Guard Column

    Guard Columns

    Guard columns are protective columns that is installed between the injector and the analytical column. Guard columns have two main functions. The first is to trap particulate matter that would otherwise block the column through a frit at the inlet. They also utilize packing material that is matched to the analytical column to trap materials that would become strongly or irreversibly bound to the analytical column.

    Guard columns often match the phase of the analytical column to protect the analytical column from irreversibly bonded compounds. For more product offerings, please visit our LC Columns page, where you will find analytical columns and matching guard columns.

    Please reach out to our support staff for questions.

    EXP Guard Column Cartridges

    Picture for category EXP Guard Column Cartridges

    IDEX Guard Columns

    Picture for category IDEX Guard Columns

    Capillary Sample Trap Columns

    Picture for category Capillary Sample Trap Columns

    Agilent AdvanceBio Desalting-RP Cartridges

    Picture for category Agilent AdvanceBio Desalting-RP Cartridges
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    Picture of CT-0205 - Direct Connect Guard Holder Fingertight, one piece

    CT-0205 - Direct Connect Guard Holder Fingertight, one piece

    CT-0205
    $492.00
    Picture of CT-0205-WAT - Direct Connect Holder w/Waters Inlet

    CT-0205-WAT - Direct Connect Holder w/Waters Inlet

    CT-0205-WAT
    $489.50
    Picture of 820999-901 - High performance ZORBAX guard fittings kit

    820999-901 - High performance ZORBAX guard fittings kit

    820999-901
    $327.00
    A-100

    A-100 - Frit SS Natural 2um 0.094 x .065 x 0.2485

    A-100
    $4.99
    A-103

    A-103 - Frit SS Black 0.5um 0.094 x .065 x 0.250

    A-103
    $4.99
    C-1000

    C-1000 - Semi-Prep Guard Column Holder

    C-1000
    $295.29
    C-128-31

    C-128-31 - Frit SS Black 0.5um

    C-128-31
    $7.54
    C-130B

    C-130B - Guard Column 2mm x 2cm

    C-130B
    $167.79
    C-408

    C-408 - Frit SS Natural 0.038 x .030 x 0.125

    C-408
    $8.30
    F-152

    F-152 - Mini MicroFilter Ferrule .015in PEEK Natural

    F-152
    $8.64
    .015", Yellow PEEK
    M-125

    M-125 - Nanofilter Capsule 1um SS 2pk

    M-125
    $83.24
    P-416

    P-416 - MicroTight Female Nut 5/16-24 PEEK Natural

    P-416
    $7.64
    Picture of P-416BLK - MicroTight Female Nut 5/16-24 PEEK Black

    P-416BLK - MicroTight Female Nut 5/16-24 PEEK Black

    P-416BLK
    $7.64
    Picture of PL1612-1102 - AdvanceBio Desalting-RP, 2.1 mm, 12.5 mm, 3/pk

    PL1612-1102 - AdvanceBio Desalting-RP, 2.1 mm, 12.5 mm, 3/pk

    PL1612-1102
    $624.00
    Picture of CT-0205-C18 - EXP Guard Cartridge, 2.1mm x 5mm, C18 3µm, 3/pk

    CT-0205-C18 - EXP Guard Cartridge, 2.1mm x 5mm, C18 3µm, 3/pk

    CT-0205-C18
    $770.00
    Picture of CT-0205-C8 - EXP Guard Cartridge, 2.1mm x 5mm, C8 3µm, 3/pk

    CT-0205-C8 - EXP Guard Cartridge, 2.1mm x 5mm, C8 3µm, 3/pk

    CT-0205-C8
    $770.00
    Picture of CT-0205-PH - EXP Guard Cartridge, 2.1mm x 5mm, Phenyl-Hexyl 3µm, 3/pk

    CT-0205-PH - EXP Guard Cartridge, 2.1mm x 5mm, Phenyl-Hexyl 3µm, 3/pk

    CT-0205-PH
    $770.00
    Picture of CT-0205-P2 - C18-P2 Guard, 2.1 x 5mm, 3um, 4/pk

    CT-0205-P2 - C18-P2 Guard, 2.1 x 5mm, 3um, 4/pk

    CT-0205-P2
    $481.63

    Guard Columns

    Subcategories
    • EXP Guard Column Cartridges
    • IDEX Guard Columns
    • Capillary Sample Trap Columns
    • Agilent AdvanceBio Desalting-RP Cartridges

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