MilliporeSigma manufactures high-quality chemicals, columns and supplies for chromatography applications. We offer their full selection of high-performance liquid chromatography columns for small and large molecule analyses. Our MilliporeSigma line also includes HPLC and UHPLC solvents with the highest purity, stability, and lot-to-lot consistency. The HPLC Plus Grade Solvents are tested for suitability in HPLC with gradient analysis, spectrophotometry, environmental testing and some LC-MS applications.